In 1637 George Joyliffe (age 16) matriculated from Wadham College, Oxford University.

In 1643 George Joyliffe (age 22) was awarded Master of Arts: Oxford University from Pembroke College, Oxford University.

Evelyn's Diary. 25 Feb 1649. Came to visit me Dr. Joyliffe (age 28), discoverer of the lymphatic vessels, and an excellent anatomist.

Evelyn's Diary. 10 Jan 1657. Came Dr. Joyliffe (age 36), that famous physician and anatomist, first detector of the lymphatic veins; also the old Marquis of Argyle (age 49), and another Scotch Earl.

Evelyn's Diary. 19 Oct 1657. I went to see divers gardens about London: returning, I saw at Dr. Joyliffe's (age 36) two Virginian rattlesnakes alive, exceeding a yard in length, small heads, slender tails, but in the middle nearly the size of my leg; when vexed, swiftly vibrating and shaking their tails, as loud as a child's rattle; this, by the collision of certain gristly skins curiously jointed, yet loose, and transparent as parchment, by which they give warning; a providential caution for other creatures to avoid them. The Doctor tried their biting on rats and mice, which they immediately killed: but their vigor must needs be much exhausted here, in another climate, and kept only in a barrel of bran.