On 01 Oct 1631 William Brereton 1st Baron Brereton (age 81) died. His grandson William Brereton 2nd Baron Brereton (age 20) succeeded 2nd Baron Brereton and inherited Brereton Hall, Cheshire [Map]. Elizabeth Goring Baroness Brereton by marriage Baroness Brereton.

In Apr 1664 William Brereton 2nd Baron Brereton (age 53) died. His son William Brereton 3rd Baron Brereton (age 32) succeeded 3rd Baron Brereton and inherited Brereton Hall, Cheshire [Map]. Frances Willoughby Baroness Brereton (age 39) by marriage Baroness Brereton.

On 17 Mar 1680 William Brereton 3rd Baron Brereton (age 48) died. His son John Brereton 4th Baron Brereton (age 20) succeeded 4th Baron Brereton and inherited Brereton Hall, Cheshire [Map].

In 1718 John Brereton 4th Baron Brereton (age 58) died without issue. His brother Francis Brereton 5th Baron Brereton (age 55) succeeded 5th Baron Brereton and inherited Brereton Hall, Cheshire [Map].

On or before 11 Apr 1722, the date he was buried at St Oswald's Church, Brereton [Map], Francis Brereton 5th Baron Brereton (age 59) died unmarried and without issue. Baron Brereton extinct.